Your search matches the following sites:
KRAS- clarientinc.com
V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog also known as KRAS is a protein which in humans is encoded by the KRAS gene. Like other members of the Ras family, the KRAS protein is a GTPase and is an early player in many signal transduction pathways. KRAS is usually tethered to cell membranes because of the presence of an isoprenyl group on its C-terminus.
Keywords:
PI3K Inhibitor- clarientinc.com
The phosphoinositide 3-kinase (PI3K)/AKT1 pathway is acknowledged as a key component of cell survival.Activated by receptors or the small GTPase Ras,the various PI3K isoforms phosphorylate inositol lipids to form second messenger phosphoinositides. PI3K family members have long been accepted as oncogenes.
Keywords:
EGFR Testing- clarientinc.com
A large body of experimental and clinical work supports the view that EGFR is a relevant target for cancer therapy. The development of selective tyrosine kinase inhibitors has become an important area of drug discovery for the treatment of a variety of solid tumors such as breast, ovarian and colorectal cancers, NSCLC, and carcinoma of the head and neck.
Keywords: